WNT11

Across TCGA patient cohorts, WNT11 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,695 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WNT11-associated proteins across cancer lineages are TLN2, PRKG1, and PSME2. Each is linked with WNT11 in more than 4 cancer types. Because this analysis shows association rather than direction, both WNT11-to-partner and partner-to-WNT11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WNT11 versus TLN2 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT11→partner) and Y-score (partner→WNT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TLN2 →	+0.520	+0.870	<.001	.001	3	5
OV	PRKG1 →	+0.485	+1.123	<.001	.009	3	4
OV	PSME2 →	-0.462	-1.492	<.001	.002	3	4
LSCC	RAB27A →	-0.416	-1.273	<.001	<.001	3	4
BRCA	RAB3D →	-0.558	-0.793	.004	.002	3	4
OV	VCL →	+0.286	+1.466	.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,695 associations by consensus.

WNT11 vs TLN2 — BRCA

Explore this scatter interactively →