WNT11

Across TCGA cell cohorts, WNT11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,139 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WNT11-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Regulation of myoblast fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with WNT11 in more than 10 cancer types. Because this analysis shows association rather than direction, both WNT11-to-partner and partner-to-WNT11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by WNT11-low versus WNT11-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT11→partner) and Y-score (partner→WNT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.172	+2.867	<.001	.001	3	11
STOMACH	Regulation of myoblast fusion →	+0.164	+3.012	<.001	<.001	3	10
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.161	+3.083	<.001	<.001	3	10
OESOPHAGUS	Schwann cell differentiation →	+0.128	+1.510	.002	.003	3	9
OESOPHAGUS	Mitochondrial electron transport, cytochrome c to oxygen →	+0.126	+1.717	<.001	<.001	3	9
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.135	+1.948	.002	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,139 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by WNT11 expression — STOMACH

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