WNT10A

Across TCGA patient cohorts, WNT10A mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible WNT10A-associated genes across cancer lineages are GMP, CMP, and Neutrophils. Each is linked with WNT10A in more than 1 cancer types. Because this analysis shows association rather than direction, both WNT10A-to-partner and partner-to-WNT10A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by WNT10A-low versus WNT10A-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT10A→partner) and Y-score (partner→WNT10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	GMP →	+0.118	+2.584	<.001	.036	3	2
UCEC	CMP →	+0.052	+2.818	.005	.037	3	1
UCEC	Neutrophils →	+0.021	+2.166	<.001	.040	3	1
SKCM	iDC →	-0.197	-2.993	.033	.037	1	1
SKCM	pro B-cells →	-0.111	-2.968	.027	.037	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

GMP by WNT10A expression — STAD

Explore this box plot interactively →