WNT10A

Across TCGA cell cohorts, WNT10A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,831 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible WNT10A-associated GO terms across cancer lineages are Negative regulation of defense response, Sebaceous gland development, and Positive regulation of protein modification by small protein conjugation or removal. Each is linked with WNT10A in more than 10 cancer types. Because this analysis shows association rather than direction, both WNT10A-to-partner and partner-to-WNT10A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of defense response grouped by WNT10A-low versus WNT10A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT10A→partner) and Y-score (partner→WNT10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of defense response →	+0.085	+1.879	<.001	.003	3	11
BLOOD_Lymphoma	Sebaceous gland development →	+1.797	+3.045	<.001	<.001	3	10
PANCREAS	Positive regulation of protein modification by small protein conjugation or removal →	+0.051	+1.573	.001	.005	3	10
OVARY	Positive regulation of bicellular tight junction assembly →	+0.267	+2.272	<.001	.001	3	10
PANCREAS	Skin development →	+0.133	+2.169	<.001	<.001	3	10
PANCREAS	Negative regulation of regulatory T cell differentiation →	+0.199	+1.936	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,831 associations by consensus.

Negative regulation of defense response by WNT10A expression — BREAST

Explore this box plot interactively →