WNT10A

Across TCGA cell cohorts, WNT10A protein abundance is significantly associated with the RNA expression of many other genes, with 2,421 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible WNT10A-associated genes across cancer lineages are ANXA9, CAPS, and SLPI. Each is linked with WNT10A in more than 6 cancer types. Because this analysis shows association rather than direction, both WNT10A-to-partner and partner-to-WNT10A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WNT10A versus ANXA9 in PANCREAS, with a Pearson correlation of -0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT10A→partner) and Y-score (partner→WNT10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	ANXA9 →	-2.536	-1.924	.002	.002	3	6
PANCREAS	CAPS →	-3.082	-1.630	<.001	.003	3	5
URINARY_TRACT	SLPI →	-5.488	-1.325	.001	.008	3	5
URINARY_TRACT	CD70 →	+4.524	+1.325	.001	.008	1	7
BREAST	GTF2H2 →	+1.216	+1.053	.002	<.001	3	5
LUNG_NSCLC_LUAD	TMEM45B →	-2.304	-1.288	.003	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,421 associations by consensus.

WNT10A vs ANXA9 — PANCREAS

Explore this scatter interactively →