Across TCGA cell cohorts, WNK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,808 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible WNK3-associated GO terms across cancer lineages are Regulation of telomerase RNA localization to Cajal body, Protein-DNA complex organization, and Transcription initiation at RNA polymerase II promoter. Each is linked with WNK3 in more than 12 cancer types. Because this analysis shows association rather than direction, both WNK3-to-partner and partner-to-WNK3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WNK3→partner) and Y-score (partner→WNK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of telomerase RNA localization to Cajal body →	+0.116	+0.833	<.001	<.001	3	13
LUNG_SCLC	Protein-DNA complex organization →	+0.074	+0.970	.001	<.001	3	12
BONE	Transcription initiation at RNA polymerase II promoter →	+0.061	+0.707	.008	.004	3	12
BONE	Positive regulation of monoatomic ion transport →	-0.147	-0.972	.005	<.001	3	12
LUNG_SCLC	Negative regulation of gene expression, epigenetic →	+0.064	+0.761	<.001	.001	3	12
BONE	Positive regulation of DNA metabolic process →	+0.068	+0.691	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,808 associations by consensus.

Exploration

WNK3 survival (RNA) · tumor vs normal (RNA) · all WNK3 data types