WNK2

Across TCGA cell cohorts, WNK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,941 significant associations in total. BONE shows the largest number of these associations.

The most reproducible WNK2-associated GO terms across cancer lineages are Regulation of coagulation, Regulation of DNA repair, and Regulation of collagen metabolic process. Each is linked with WNK2 in more than 13 cancer types. Because this analysis shows association rather than direction, both WNK2-to-partner and partner-to-WNK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of coagulation grouped by WNK2-low versus WNK2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WNK2→partner) and Y-score (partner→WNK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of coagulation →	-0.193	-1.715	<.001	<.001	3	14
LIVER	Regulation of DNA repair →	+0.079	+4.267	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Regulation of collagen metabolic process →	-0.184	-2.237	.002	.002	3	13
SOFT_TISSUE	Regulation of hemostasis →	-0.186	-1.697	<.001	<.001	3	13
OESOPHAGUS	Regulation of mRNA stability →	+0.050	+1.348	<.001	.001	3	12
LIVER	mRNA stabilization →	+0.109	+3.344	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,941 associations by consensus.

Regulation of coagulation by WNK2 expression — SOFT_TISSUE

Explore this box plot interactively →