WLS

Across TCGA patient cohorts, WLS RNA expression is significantly associated with the protein abundance of many other proteins, with 14,305 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible WLS-associated proteins across cancer lineages are DDX21_S89, DOCK2_S1685, and ESF1_S153. Each is linked with WLS in more than 4 cancer types. Because this analysis shows association rather than direction, both WLS-to-partner and partner-to-WLS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WLS versus DDX21_S89 in LUAD, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WLS→partner) and Y-score (partner→WLS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DDX21_S89 →	-1.068	-0.869	<.001	<.001	3	5
CCRCC	DOCK2_S1685 →	-0.457	-0.794	<.001	.001	3	5
LUAD	ESF1_S153 →	-0.796	-0.964	.001	<.001	3	5
BRCA	SBF2 →	+0.269	+0.960	<.001	<.001	3	5
BRCA	BDH2 →	+0.459	+1.147	<.001	<.001	3	5
LUAD	MZB1 →	-0.880	-0.778	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,305 associations by consensus.

WLS vs DDX21_S89 — LUAD

Explore this scatter interactively →