WIPI2

Across TCGA patient cohorts, WIPI2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,368 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WIPI2-associated proteins across cancer lineages are FOXK1, BAG6, and FBXL18. Each is linked with WIPI2 in more than 7 cancer types. Because this analysis shows association rather than direction, both WIPI2-to-partner and partner-to-WIPI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WIPI2 versus FOXK1 in LUAD, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WIPI2→partner) and Y-score (partner→WIPI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FOXK1 →	+0.312	+0.460	<.001	<.001	3	8
PDAC	BAG6 →	+0.205	+0.272	<.001	<.001	3	6
OV	FBXL18 →	+0.376	+0.569	<.001	<.001	3	6
PDAC	FOXK1_S213 →	+0.518	+0.244	.002	.004	3	5
LUAD	SPCS3 →	-0.648	-0.526	<.001	<.001	3	5
LUAD	C7orf50 →	+0.435	+0.434	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,368 associations by consensus.

WIPI2 vs FOXK1 — LUAD

Explore this scatter interactively →