WIPI2

Across TCGA cell cohorts, WIPI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,512 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible WIPI2-associated GO terms across cancer lineages are Meiotic mismatch repair, Endosomal transport, and Macroautophagy. Each is linked with WIPI2 in more than 15 cancer types. Because this analysis shows association rather than direction, both WIPI2-to-partner and partner-to-WIPI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic mismatch repair grouped by WIPI2-low versus WIPI2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WIPI2→partner) and Y-score (partner→WIPI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Meiotic mismatch repair →	+0.150	+0.742	<.001	<.001	3	16
SOFT_TISSUE	Endosomal transport →	+0.065	+0.821	<.001	<.001	3	15
STOMACH	Macroautophagy →	+0.073	+0.575	<.001	.002	3	15
SOFT_TISSUE	Autophagosome organization →	+0.055	+0.662	<.001	<.001	3	14
STOMACH	Regulation of transcription initiation by RNA polymerase II →	+0.070	+0.923	<.001	<.001	3	14
STOMACH	Protein polyubiquitination →	+0.058	+0.792	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,512 associations by consensus.

Meiotic mismatch repair by WIPI2 expression — BREAST

Explore this box plot interactively →