WIPF3

Across TCGA cell cohorts, WIPF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,087 significant associations in total. BONE shows the largest number of these associations.

The most reproducible WIPF3-associated GO terms across cancer lineages are ATP synthesis coupled electron transport, Mitochondrial ATP synthesis coupled electron transport, and Cytoplasmic translation. Each is linked with WIPF3 in more than 12 cancer types. Because this analysis shows association rather than direction, both WIPF3-to-partner and partner-to-WIPF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP synthesis coupled electron transport grouped by WIPF3-low versus WIPF3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WIPF3→partner) and Y-score (partner→WIPF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	ATP synthesis coupled electron transport →	+0.111	+1.161	.003	.001	3	13
LUNG_NSCLC_LUSC	Mitochondrial ATP synthesis coupled electron transport →	+0.111	+1.161	.003	.001	3	13
BREAST	Cytoplasmic translation →	+0.076	+0.438	<.001	.006	3	12
BLOOD_Myeloma	Proton motive force-driven mitochondrial ATP synthesis →	+0.072	+0.819	.004	.009	3	11
LUNG_NSCLC_LUAD	Proton motive force-driven ATP synthesis →	+0.071	+0.671	<.001	<.001	2	12
LUNG_NSCLC_LUSC	Aerobic electron transport chain →	+0.111	+1.147	.002	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,087 associations by consensus.

ATP synthesis coupled electron transport by WIPF3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →