WIPF2

Across TCGA pan-cancer cohorts, WIPF2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated WIPF2 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher WIPF2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated WIPF2 expression acts as an unfavorable survival marker, although some lineages such as COAD and UCEC show a favorable association.

COAD, LUAD, and UCEC are the cancer types where WIPF2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.915	.009	90	view →
LUAD	DFS	Tertile	All	0.370	0.938	<.001	23	view →
UCEC	DFS	Quartile	All	0.970	0.715	.008	10	view →
LSCC	DFS	Quartile	II,III,IV	0.322	1.000	.024	6	view →
CCRCC	DFS	Tertile	IV	0.758	0.099	.024	6	view →
GBM	DFS	Quartile	All	0.215	0.486	.037	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

WIPF2–COAD (DFS)

Open the COAD breakdown →