WIPF2

Across TCGA patient cohorts, WIPF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,555 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WIPF2-associated proteins across cancer lineages are FLI1_S39, TBC1D2B_S155, and BUB3. Each is linked with WIPF2 in more than 4 cancer types. Because this analysis shows association rather than direction, both WIPF2-to-partner and partner-to-WIPF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WIPF2 versus FLI1_S39 in LSCC, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WIPF2→partner) and Y-score (partner→WIPF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FLI1_S39 →	-0.463	-0.302	<.001	<.001	3	5
LSCC	TBC1D2B_S155 →	-0.353	-0.336	.001	.001	3	5
PDAC	BUB3 →	+0.239	+0.408	<.001	<.001	3	4
LSCC	CARS1 →	-0.270	-0.430	<.001	<.001	3	4
OV	CFL1_S24 →	-1.429	-0.569	<.001	.003	3	4
HNSC	CSTF1 →	+0.185	+0.391	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,555 associations by consensus.

WIPF2 vs FLI1_S39 — LSCC

Explore this scatter interactively →