WIPF2

Across TCGA patient cohorts, WIPF2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,368 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible WIPF2-associated genes across cancer lineages are CDS1, PLEKHO1, and WASL. Each is linked with WIPF2 in more than 5 cancer types. Because this analysis shows association rather than direction, both WIPF2-to-partner and partner-to-WIPF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WIPF2 versus CDS1 in HNSC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WIPF2→partner) and Y-score (partner→WIPF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CDS1 →	+0.773	+0.317	.001	<.001	3	6
HNSC	PLEKHO1 →	-0.801	-0.394	<.001	<.001	3	6
HNSC	WASL →	+0.693	+0.286	<.001	<.001	3	6
HNSC	SBDS →	+0.829	+0.243	.004	.002	3	5
OV	ZCCHC18 →	-0.556	-0.270	.001	.002	3	5
BRCA	CISD3 →	+0.596	+0.358	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,368 associations by consensus.

WIPF2 vs CDS1 — HNSC

Explore this scatter interactively →