WIPF2

Across TCGA cell cohorts, WIPF2 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WIPF2-associated genes across cancer lineages are AVP, BANF2, and DEFB129. Each is linked with WIPF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both WIPF2-to-partner and partner-to-WIPF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by WIPF2-low versus WIPF2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WIPF2→partner) and Y-score (partner→WIPF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.039	+5.794	<.001	<.001	3	1
BLOOD_Lymphoma	BANF2 →	+0.035	+4.643	.003	.005	3	1
BLOOD_Lymphoma	DEFB129 →	+0.032	+5.247	<.001	.001	3	1
BLOOD_Lymphoma	CEACAM3 →	+0.075	+4.927	.007	.001	3	1
BLOOD_Lymphoma	MROH2B →	+0.063	+4.643	<.001	.005	3	1
BLOOD_Leukemia	OR6P1 →	+0.012	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

AVP by WIPF2 expression — BLOOD_Lymphoma

Explore this box plot interactively →