WIPF1

Across TCGA pan-cancer cohorts, WIPF1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated WIPF1 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher WIPF1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated WIPF1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD, COAD, and HNSC are the cancer types where WIPF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.777	0.468	.004	16	view →
COAD	DFS	Tertile	III,IV	0.865	1.000	.048	12	view →
HNSC	DFS	Median	II,III,IV	0.560	0.762	.020	11	view →
CCRCC	DFS	Tertile	II,III,IV	0.751	0.420	.014	9	view →
PDAC	OS	Tertile	IV	0.836	0.455	.024	7	view →
GBM	DFS	Quartile	All	0.192	0.437	.006	5	view →
LSCC	OS	Quartile	III,IV	1.000	0.659	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

WIPF1–LUAD (DFS)

Open the LUAD breakdown →