WIPF1

Across TCGA patient cohorts, WIPF1 protein abundance is significantly associated with the RNA expression of many other genes, with 20,230 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WIPF1-associated genes across cancer lineages are CYTH4, GRAP2, and NCF4. Each is linked with WIPF1 in more than 9 cancer types. Because this analysis shows association rather than direction, both WIPF1-to-partner and partner-to-WIPF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WIPF1 versus CYTH4 in GBM, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WIPF1→partner) and Y-score (partner→WIPF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+1.177	+0.454	<.001	<.001	3	10
BRCA	GRAP2 →	+0.722	+0.381	<.001	<.001	3	10
GBM	NCF4 →	+1.283	+0.486	<.001	<.001	3	10
GBM	CSF2RB →	+1.162	+0.473	<.001	<.001	3	10
HNSC	SIRPB1 →	+0.717	+0.560	<.001	<.001	3	10
GBM	TLR8 →	+1.276	+0.435	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,230 associations by consensus.

WIPF1 vs CYTH4 — GBM

Explore this scatter interactively →