WIF1

Across TCGA patient cohorts, WIF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,980 significant associations in total. GBM shows the largest number of these associations.

The most reproducible WIF1-associated proteins across cancer lineages are PLCB4, SBSPON, and MYH14. Each is linked with WIF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both WIF1-to-partner and partner-to-WIF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WIF1 versus PLCB4 in HNSC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WIF1→partner) and Y-score (partner→WIF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PLCB4 →	+0.643	+1.757	<.001	<.001	3	5
BRCA	SBSPON →	+0.785	+0.869	<.001	.003	3	5
HNSC	MYH14 →	+0.567	+0.805	<.001	.007	3	4
GBM	NMI →	-0.410	-1.280	<.001	<.001	3	4
GBM	PARP14 →	-0.371	-1.304	<.001	<.001	3	4
GBM	RGCC →	+0.630	+1.165	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,980 associations by consensus.

WIF1 vs PLCB4 — HNSC

Explore this scatter interactively →