WHRN

Across TCGA cell cohorts, WHRN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,626 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible WHRN-associated GO terms across cancer lineages are Purine nucleoside triphosphate metabolic process, Purine ribonucleoside triphosphate metabolic process, and Negative regulation of myoblast fusion. Each is linked with WHRN in more than 12 cancer types. Because this analysis shows association rather than direction, both WHRN-to-partner and partner-to-WHRN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine nucleoside triphosphate metabolic process grouped by WHRN-low versus WHRN-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WHRN→partner) and Y-score (partner→WHRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Purine nucleoside triphosphate metabolic process →	+0.088	+1.497	<.001	<.001	3	13
BONE	Purine ribonucleoside triphosphate metabolic process →	+0.086	+1.508	<.001	<.001	3	13
STOMACH	Negative regulation of myoblast fusion →	+0.144	+2.285	.002	.001	3	13
BONE	Calcium-independent cell-matrix adhesion →	+0.225	+1.701	<.001	<.001	3	13
STOMACH	Response to starvation →	+0.059	+1.751	.002	.001	3	13
KIDNEY	Regulation of myoblast fusion →	+0.111	+1.551	.002	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,626 associations by consensus.

Purine nucleoside triphosphate metabolic process by WHRN expression — BONE

Explore this box plot interactively →