Across TCGA patient cohorts, WFDC9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,834 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WFDC9-associated GO terms across cancer lineages are Signal peptide processing, Nucleobase biosynthetic process, and Positive regulation of amyloid-beta formation. Each is linked with WFDC9 in more than 6 cancer types. Because this analysis shows association rather than direction, both WFDC9-to-partner and partner-to-WFDC9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC9→partner) and Y-score (partner→WFDC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Signal peptide processing →	+0.046	+0.020	<.001	<.001	3	7
STAD	Nucleobase biosynthetic process →	+0.055	+0.139	<.001	.001	3	6
STAD	Positive regulation of amyloid-beta formation →	+0.050	+0.128	<.001	.002	3	6
STAD	Regulation of polysaccharide metabolic process →	+0.042	+0.131	<.001	<.001	3	6
HNSC	Spermidine metabolic process →	+0.049	+0.019	<.001	<.001	3	5
STAD	Acinar cell differentiation →	+0.063	+0.117	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,834 associations by consensus.

Exploration

WFDC9 survival (RNA) · tumor vs normal (RNA) · all WFDC9 data types