WFDC9

Across TCGA cell cohorts, WFDC9 RNA expression is significantly associated with the go_rna of many other GO terms, with 95 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WFDC9-associated GO terms across cancer lineages are Regulation of circadian sleep/wake cycle, wakefulness, Neurotransmitter uptake, and Regulation of mitophagy. Each is linked with WFDC9 in more than 1 cancer types. Because this analysis shows association rather than direction, both WFDC9-to-partner and partner-to-WFDC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of circadian sleep/wake cycle, wakefulness grouped by WFDC9-low versus WFDC9-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC9→partner) and Y-score (partner→WFDC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of circadian sleep/wake cycle, wakefulness →	-0.118	-0.103	.006	.008	3	1
LARGE_INTESTINE	Neurotransmitter uptake →	-0.124	-0.147	<.001	.008	3	1
LARGE_INTESTINE	Regulation of mitophagy →	-0.047	-0.104	.001	.007	3	1
LARGE_INTESTINE	Calcium ion export →	-0.507	-0.112	.002	.004	3	1
LARGE_INTESTINE	Positive regulation of muscle tissue development →	+0.137	+0.132	<.001	.004	3	1
LARGE_INTESTINE	Negative regulation of leukocyte differentiation →	+0.052	+0.107	.009	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 95 associations by consensus.

Regulation of circadian sleep/wake cycle, wakefulness by WFDC9 expression — LARGE_INTESTINE

Explore this box plot interactively →