WFDC3

Across TCGA patient cohorts, WFDC3 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WFDC3-associated genes across cancer lineages are CD8+ Tem and Neurons. Each is linked with WFDC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both WFDC3-to-partner and partner-to-WFDC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tem grouped by WFDC3-low versus WFDC3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC3→partner) and Y-score (partner→WFDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tem →	+0.003	+4.606	<.001	.044	3	1
UCEC	Neurons →	-0.022	-3.129	.018	.019	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ Tem by WFDC3 expression — UCEC

Explore this box plot interactively →