WFDC2

Across TCGA cell cohorts, WFDC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,069 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible WFDC2-associated GO terms across cancer lineages are Positive regulation of lung ciliated cell differentiation, Regulation of lung ciliated cell differentiation, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with WFDC2 in more than 13 cancer types. Because this analysis shows association rather than direction, both WFDC2-to-partner and partner-to-WFDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of lung ciliated cell differentiation grouped by WFDC2-low versus WFDC2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC2→partner) and Y-score (partner→WFDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of lung ciliated cell differentiation →	+1.845	+5.614	<.001	<.001	3	14
OVARY	Regulation of lung ciliated cell differentiation →	+1.973	+5.614	<.001	<.001	3	13
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.101	+4.372	<.001	<.001	3	11
STOMACH	Regulation of myoblast fusion →	+0.128	+3.369	.003	.004	3	11
URINARY_TRACT	Negative regulation of mRNA metabolic process →	+0.063	+3.298	.001	.001	3	10
BREAST	Regulation of mRNA processing →	+0.096	+3.898	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,069 associations by consensus.

Positive regulation of lung ciliated cell differentiation by WFDC2 expression — OVARY

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