WFDC1

Across TCGA cell cohorts, WFDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,392 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible WFDC1-associated GO terms across cancer lineages are NMDA glutamate receptor clustering, Sterol transport, and Regulation of tumor necrosis factor-mediated signaling pathway. Each is linked with WFDC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both WFDC1-to-partner and partner-to-WFDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NMDA glutamate receptor clustering grouped by WFDC1-low versus WFDC1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC1→partner) and Y-score (partner→WFDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	NMDA glutamate receptor clustering →	+0.916	+3.142	<.001	<.001	3	6
SKIN	Sterol transport →	+0.050	+2.095	.002	.006	3	4
CNS	Regulation of tumor necrosis factor-mediated signaling pathway →	-0.038	-1.114	.004	.003	3	4
BLOOD_Leukemia	Dopamine metabolic process →	+0.075	+0.895	.007	.001	3	4
BLOOD_Leukemia	Tricarboxylic acid cycle →	+0.046	+0.554	.001	.007	3	4
SKIN	Triglyceride-rich lipoprotein particle clearance →	+1.007	+2.848	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,392 associations by consensus.

NMDA glutamate receptor clustering by WFDC1 expression — SKIN

Explore this box plot interactively →