WDTC1

Across TCGA patient cohorts, WDTC1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,725 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible WDTC1-associated genes across cancer lineages are SMIM14, TMEM50A, and F8. Each is linked with WDTC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both WDTC1-to-partner and partner-to-WDTC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDTC1 versus SMIM14 in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDTC1→partner) and Y-score (partner→WDTC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SMIM14 →	+0.844	+0.151	.002	.003	3	5
OV	TMEM50A →	+0.512	+0.289	<.001	.001	3	5
LUAD	F8 →	+0.572	+0.231	<.001	<.001	3	5
PDAC	ALB →	+1.663	+0.243	<.001	.002	3	4
UCEC	HASPIN →	-0.665	-0.201	<.001	<.001	3	4
UCEC	AURKB →	-1.165	-0.184	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,725 associations by consensus.

WDTC1 vs SMIM14 — BRCA

Explore this scatter interactively →