Across TCGA pan-cancer cohorts, WDSUB1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated WDSUB1 data layer compared with 17 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher WDSUB1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated WDSUB1 expression acts as an unfavorable survival marker.

LUSC, UCEC, and ACC are the cancer types where WDSUB1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	All	0.202	0.712	.008	21	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: WDSUB1 tumor-vs-normal RNA expression · all WDSUB1 data types