WDR93

Across TCGA pan-cancer cohorts, WDR93 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated WDR93 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher WDR93 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated WDR93 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUSC, LIHC, and LGG are the cancer types where WDR93 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	All	0.097	0.779	<.001	36	view →
LIHC	DFS	Median	All	0.068	0.555	<.001	12	view →
LGG	OS	Median	All	0.407	0.811	.037	6	view →
UCEC	DFS	Median	II,III,IV	0.915	0.436	.028	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

WDR93–LUSC (OS)

Open the LUSC breakdown →