WDR92

Across TCGA pan-cancer cohorts, WDR92 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated WDR92 data layer compared with 21 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher WDR92 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated WDR92 expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

CCRCC, LSCC, and UCEC are the cancer types where WDR92 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.447	0.740	.006	12	view →
LSCC	DFS	Tertile	II,III,IV	0.847	0.496	.018	8	view →
UCEC	OS	Median	All	0.835	0.980	.003	6	view →
HNSC	OS	Quartile	All	0.818	0.942	.029	6	view →
PDAC	OS	Median	IV	0.951	0.381	.006	6	view →
LUAD	OS	Median	All	0.681	0.853	.025	5	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

WDR92–CCRCC (DFS)

Open the CCRCC breakdown →