WDR90

Across TCGA pan-cancer cohorts, WDR90 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated WDR90 data layer compared with 20 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher WDR90 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated WDR90 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LSCC and LUAD are the cancer types where WDR90 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	All	0.845	1.000	.013	15	view →
LUAD	DFS	Median	All	0.827	0.358	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

WDR90–LSCC (DFS)

Open the LSCC breakdown →