WDR89

Across TCGA patient cohorts, WDR89 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,001 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDR89-associated proteins across cancer lineages are MTHFD1, YLPM1, and TRMT5. Each is linked with WDR89 in more than 8 cancer types. Because this analysis shows association rather than direction, both WDR89-to-partner and partner-to-WDR89 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR89 versus MTHFD1 in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR89→partner) and Y-score (partner→WDR89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MTHFD1 →	+0.397	+0.471	<.001	<.001	3	9
GBM	YLPM1 →	+0.325	+0.451	<.001	<.001	3	7
GBM	TRMT5 →	+0.353	+0.433	<.001	<.001	3	7
HNSC	DNTTIP1 →	+0.326	+0.741	<.001	<.001	3	7
GBM	ZC3H14 →	+0.237	+0.410	<.001	<.001	3	6
GBM	PPP2R5E →	+0.353	+0.592	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,001 associations by consensus.

WDR89 vs MTHFD1 — GBM

Explore this scatter interactively →