WDR89

Across TCGA patient cohorts, WDR89 mutation is significantly associated with the RNA expression of many other genes, with 1,953 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR89-associated genes across cancer lineages are C4A-AS1, RPSAP68, and IRF2-DT. Each is linked with WDR89 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR89-to-partner and partner-to-WDR89 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C4A-AS1 grouped by WDR89-low versus WDR89-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR89→partner) and Y-score (partner→WDR89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	C4A-AS1 →	+0.019	+7.741	<.001	.009	3	2
COAD	RPSAP68 →	+0.099	+7.741	<.001	.009	3	2
UCEC	IRF2-DT →	-0.481	-3.678	.001	.001	3	1
UCEC	SNORD11B →	+0.617	+2.476	<.001	.001	3	1
UCEC	RNU4-5P →	+0.417	+2.113	<.001	.007	3	1
UCEC	ZNHIT3 →	+0.553	+3.721	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,953 associations by consensus.

C4A-AS1 by WDR89 expression — COAD

Explore this box plot interactively →