WDR82

Across TCGA pan-cancer cohorts, WDR82 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of WDR82’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where WDR82 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types WDR82 is over-expressed in tumor, although a few such as PDAC show the opposite, repressed pattern.

COAD, LSCC, and LUAD are the cancer types where WDR82 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in WDR82 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	+0.196	<.001	10	view →
LSCC	Male	II,III,IV	+0.212	<.001	8	view →
LUAD	Male	All	+0.155	<.001	6	view →
PDAC	Female	II,III,IV	−0.294	.012	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

WDR82–COAD

Open the COAD breakdown →