WDR81

Across TCGA pan-cancer cohorts, WDR81 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated WDR81 data layer compared with 23 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher WDR81 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated WDR81 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, UCEC, and LUAD are the cancer types where WDR81 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	IV	0.785	0.123	.009	30	view →
UCEC	OS	Quartile	II,III,IV	0.541	1.000	.029	12	view →
LUAD	DFS	Quartile	All	0.772	0.460	.012	3	view →
HNSC	OS	Quartile	All	0.849	0.650	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

WDR81–CCRCC (OS)

Open the CCRCC breakdown →