WDR77

Across TCGA patient cohorts, WDR77 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,419 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDR77-associated proteins across cancer lineages are TRIM33, ZMYM2, and MTA2. Each is linked with WDR77 in more than 6 cancer types. Because this analysis shows association rather than direction, both WDR77-to-partner and partner-to-WDR77 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR77 versus TRIM33 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR77→partner) and Y-score (partner→WDR77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM33 →	+0.371	+0.384	<.001	<.001	3	7
LSCC	ZMYM2 →	+0.296	+0.445	.005	<.001	3	5
GBM	MTA2 →	+0.344	+0.326	<.001	<.001	3	5
GBM	P4HB →	-0.373	-0.246	<.001	<.001	3	5
OV	PRMT5 →	+0.350	+0.603	.003	.006	2	6
BRCA	TRIM33_S862 →	+0.992	+0.421	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,419 associations by consensus.

WDR77 vs TRIM33 — GBM

Explore this scatter interactively →