WDR77

Across TCGA patient cohorts, WDR77 protein abundance is significantly associated with the RNA expression of many other genes, with 14,542 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDR77-associated genes across cancer lineages are PRMT5, DCAF11, and DHRS4-AS1. Each is linked with WDR77 in more than 8 cancer types. Because this analysis shows association rather than direction, both WDR77-to-partner and partner-to-WDR77 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR77 versus PRMT5 in LSCC, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR77→partner) and Y-score (partner→WDR77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PRMT5 →	+0.798	+0.315	<.001	<.001	3	9
LUAD	DCAF11 →	+0.452	+0.241	<.001	<.001	3	7
COAD	DHRS4-AS1 →	+0.584	+0.241	<.001	<.001	3	7
LSCC	NOP9 →	+0.526	+0.254	<.001	<.001	3	7
BRCA	ZNF839 →	+0.509	+0.201	<.001	.001	3	7
LUAD	AP4S1 →	+0.512	+0.159	<.001	.005	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,542 associations by consensus.

WDR77 vs PRMT5 — LSCC

Explore this scatter interactively →