WDR72

Across TCGA patient cohorts, WDR72 mutation is significantly associated with the total protein of many other genes, with 56 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR72-associated genes across cancer lineages are 4E-BP1, Raptor, and FASN. Each is linked with WDR72 in more than 3 cancer types. Because this analysis shows association rather than direction, both WDR72-to-partner and partner-to-WDR72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 4E-BP1 grouped by WDR72-low versus WDR72-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR72→partner) and Y-score (partner→WDR72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.377	+3.700	<.001	.001	3	4
LUSC	Raptor →	+0.195	+2.825	.016	.033	3	3
UCEC	FASN →	+0.294	+1.662	.035	.011	3	3
UCEC	INPP4B →	-0.289	-2.906	.011	.001	3	3
UCEC	ATM →	-0.447	-1.861	.005	.049	3	3
SKCM	AR →	-0.130	-2.000	.010	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

4E-BP1 by WDR72 expression — UCEC

Explore this box plot interactively →