WDR72

Across TCGA cell cohorts, WDR72 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,824 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible WDR72-associated GO terms across cancer lineages are Response to prostaglandin D, Cellular response to prostaglandin D stimulus, and Response to endoplasmic reticulum stress. Each is linked with WDR72 in more than 7 cancer types. Because this analysis shows association rather than direction, both WDR72-to-partner and partner-to-WDR72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to prostaglandin D grouped by WDR72-low versus WDR72-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR72→partner) and Y-score (partner→WDR72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Response to prostaglandin D →	+0.964	+2.394	.001	.002	2	8
LUNG_NSCLC_LUSC	Cellular response to prostaglandin D stimulus →	+0.964	+2.394	.001	.002	2	8
URINARY_TRACT	Response to endoplasmic reticulum stress →	+0.086	+2.623	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Calcium ion transmembrane transport →	-0.056	-1.413	.001	.007	3	6
STOMACH	mRNA 3'-end processing →	+0.078	+1.804	.001	.002	3	6
CNS	Negative regulation of synaptic transmission, GABAergic →	-0.323	-0.957	.007	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,824 associations by consensus.

Response to prostaglandin D by WDR72 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →