WDR72

Across TCGA cell cohorts, WDR72 mutation is significantly associated with the RNA expression of many other genes, with 474 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR72-associated genes across cancer lineages are INSL5, NANOGNB, and MROH5. Each is linked with WDR72 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR72-to-partner and partner-to-WDR72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INSL5 grouped by WDR72-low versus WDR72-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR72→partner) and Y-score (partner→WDR72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	INSL5 →	+0.022	+2.938	.002	.004	3	2
BLOOD_Lymphoma	NANOGNB →	+0.021	+3.472	<.001	.002	3	2
BLOOD_Lymphoma	MROH5 →	+0.011	+3.129	.002	.002	3	2
LUNG_NSCLC_LUAD	XAGE3 →	+0.128	+4.215	<.001	.002	3	2
STOMACH	DEFB132 →	+0.084	+4.285	<.001	.007	3	2
LARGE_INTESTINE	KLRG1 →	+0.650	+3.169	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 474 associations by consensus.

INSL5 by WDR72 expression — BLOOD_Lymphoma

Explore this box plot interactively →