WDR7

Across TCGA patient cohorts, WDR7 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,413 significant associations in total. GBM shows the largest number of these associations.

The most reproducible WDR7-associated proteins across cancer lineages are SMAD4, RPL7A, and YME1L1. Each is linked with WDR7 in more than 6 cancer types. Because this analysis shows association rather than direction, both WDR7-to-partner and partner-to-WDR7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR7 versus SMAD4 in LSCC, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR7→partner) and Y-score (partner→WDR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SMAD4 →	+0.240	+0.349	<.001	<.001	3	7
GBM	RPL7A →	-0.447	-0.324	<.001	<.001	3	6
PDAC	YME1L1 →	-0.331	-0.356	<.001	<.001	3	6
HNSC	CLPX →	-0.248	-0.602	<.001	<.001	3	6
OV	MRPS5 →	-0.365	-0.692	<.001	.001	3	5
GBM	RPL3 →	-0.464	-0.390	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,413 associations by consensus.

WDR7 vs SMAD4 — LSCC

Explore this scatter interactively →