WDR7

Across TCGA patient cohorts, WDR7 protein abundance is significantly associated with the RNA expression of many other genes, with 17,303 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDR7-associated genes across cancer lineages are SLC31A2, TLR8, and CRTAM. Each is linked with WDR7 in more than 6 cancer types. Because this analysis shows association rather than direction, both WDR7-to-partner and partner-to-WDR7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR7 versus SLC31A2 in GBM, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR7→partner) and Y-score (partner→WDR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC31A2 →	+0.586	+0.260	.001	.003	3	7
HNSC	TLR8 →	+1.033	+0.241	<.001	<.001	3	7
CCRCC	CRTAM →	+0.801	+0.111	.003	.008	2	7
HNSC	ARHGAP9 →	+0.844	+0.235	<.001	<.001	3	6
COAD	STX11 →	+0.632	+0.155	<.001	<.001	3	6
COAD	FCGR2A →	+0.810	+0.179	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,303 associations by consensus.

WDR7 vs SLC31A2 — GBM

Explore this scatter interactively →