WDR62

Across TCGA pan-cancer cohorts, WDR62 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated WDR62 data layer compared with 28 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher WDR62 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated WDR62 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC, LSCC, and LUAD are the cancer types where WDR62 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	0.778	0.496	.014	10	view →
LSCC	OS	Tertile	III,IV	0.583	0.995	.024	4	view →
LUAD	OS	Tertile	III,IV	0.299	0.821	.024	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

WDR62–HNSC (DFS)

Open the HNSC breakdown →