WDR62

Across TCGA patient cohorts, WDR62 mutation is significantly associated with the RNA expression of many other genes, with 4,866 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR62-associated genes across cancer lineages are DRG1, MIR1302-5, and PRMT5. Each is linked with WDR62 in more than 4 cancer types. Because this analysis shows association rather than direction, both WDR62-to-partner and partner-to-WDR62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DRG1 grouped by WDR62-low versus WDR62-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR62→partner) and Y-score (partner→WDR62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DRG1 →	+0.235	+2.233	.003	<.001	3	5
LIHC	MIR1302-5 →	+0.247	+6.305	<.001	.001	3	4
COAD	PRMT5 →	+0.492	+3.489	.002	.002	3	4
UCEC	SSR1 →	+0.285	+1.917	.006	.001	3	4
UCEC	TOM1L1 →	+0.412	+1.191	.002	.004	3	4
COAD	BEND3 →	+0.530	+3.489	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,866 associations by consensus.

DRG1 by WDR62 expression — UCEC

Explore this box plot interactively →