WDR62

Across TCGA cell cohorts, WDR62 mutation is significantly associated with the RNA expression of many other genes, with 551 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR62-associated genes across cancer lineages are ZNF232, CUEDC2, and ACBD5. Each is linked with WDR62 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR62-to-partner and partner-to-WDR62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF232 grouped by WDR62-low versus WDR62-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR62→partner) and Y-score (partner→WDR62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZNF232 →	+0.752	+2.628	<.001	.002	3	3
LARGE_INTESTINE	CUEDC2 →	+0.600	+3.386	<.001	.001	3	2
LARGE_INTESTINE	ACBD5 →	+0.805	+3.743	<.001	<.001	3	2
LARGE_INTESTINE	TRIM37 →	+0.660	+3.743	<.001	<.001	3	2
LARGE_INTESTINE	TTC19 →	+0.847	+2.628	<.001	.002	3	2
LARGE_INTESTINE	ALKBH7 →	+0.446	+2.628	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 551 associations by consensus.

ZNF232 by WDR62 expression — LARGE_INTESTINE

Explore this box plot interactively →