Across TCGA patient cohorts, WDR5B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,979 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDR5B-associated proteins across cancer lineages are HMCES, UBXN7, and NIT2. Each is linked with WDR5B in more than 6 cancer types. Because this analysis shows association rather than direction, both WDR5B-to-partner and partner-to-WDR5B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR5B→partner) and Y-score (partner→WDR5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HMCES →	+0.531	+0.537	.001	<.001	3	6
LSCC	UBXN7 →	+0.383	+0.615	<.001	<.001	3	6
PDAC	NIT2 →	+0.370	+0.341	<.001	.001	2	7
HNSC	PCNP →	+0.366	+0.623	<.001	<.001	3	6
HNSC	ADNP →	+0.399	+0.851	<.001	<.001	3	5
OV	MSI2 →	+0.453	+0.472	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,979 associations by consensus.

Exploration

WDR5B survival (RNA) · tumor vs normal (RNA) · all WDR5B data types