WDR54

Across TCGA patient cohorts, WDR54 protein abundance is significantly associated with the RNA expression of many other genes, with 10,554 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible WDR54-associated genes across cancer lineages are OSCP1, C9orf116, and DYNLRB2. Each is linked with WDR54 in more than 6 cancer types. Because this analysis shows association rather than direction, both WDR54-to-partner and partner-to-WDR54 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR54 versus OSCP1 in BRCA, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR54→partner) and Y-score (partner→WDR54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OSCP1 →	+0.939	+0.478	<.001	<.001	3	7
UCEC	C9orf116 →	+1.373	+0.483	<.001	<.001	3	7
UCEC	DYNLRB2 →	+1.759	+0.624	<.001	<.001	3	7
BRCA	SAMD15 →	+1.198	+0.416	<.001	<.001	3	7
UCEC	CCDC113 →	+1.344	+0.534	<.001	<.001	3	7
UCEC	BBOF1 →	+0.981	+0.443	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,554 associations by consensus.

WDR54 vs OSCP1 — BRCA

Explore this scatter interactively →