WDR5

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, WDR5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,857 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible WDR5-associated GO terms across cancer lineages are Mitotic chromosome condensation, DNA-templated transcription elongation, and Protein import into nucleus. Each is linked with WDR5 in more than 18 cancer types. Because this analysis shows association rather than direction, both WDR5-to-partner and partner-to-WDR5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR5→partner) and Y-score (partner→WDR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASMitotic chromosome condensation →+0.183+0.966<.001<.001319
SOFT_TISSUEDNA-templated transcription elongation →+0.094+0.985<.001<.001318
STOMACHProtein import into nucleus →+0.089+0.612<.001.005318
SOFT_TISSUEImmunoglobulin heavy chain V-D-J recombination →+0.225+1.029<.001<.001318
UPPER_AERODIGESTIVE_TRACTRegulation of chromosome segregation →+0.135+0.798<.001.001318
SOFT_TISSUERegulation of chromosome condensation →+0.150+0.716<.001<.001318
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,857 associations by consensus.

Exploration