WDR49

Across TCGA cell cohorts, WDR49 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,232 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WDR49-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Protein stabilization, and Cilium-dependent cell motility. Each is linked with WDR49 in more than 5 cancer types. Because this analysis shows association rather than direction, both WDR49-to-partner and partner-to-WDR49 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by WDR49-low versus WDR49-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR49→partner) and Y-score (partner→WDR49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Cilium or flagellum-dependent cell motility →	-0.028	-0.682	.002	.003	3	6
BLOOD_Leukemia	Protein stabilization →	+0.023	+0.815	.003	.004	3	6
BLOOD_Leukemia	Cilium-dependent cell motility →	-0.028	-0.682	.002	.003	3	6
BLOOD_Leukemia	Flagellated sperm motility →	-0.044	-0.889	<.001	<.001	3	5
BLOOD_Leukemia	Cilium movement involved in cell motility →	-0.041	-0.717	<.001	.002	3	5
BLOOD_Leukemia	Sperm motility →	-0.044	-0.889	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,232 associations by consensus.

Cilium or flagellum-dependent cell motility by WDR49 expression — BLOOD_Leukemia

Explore this box plot interactively →