WDR47

Across TCGA pan-cancer cohorts, WDR47 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated WDR47 data layer compared with 27 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher WDR47 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated WDR47 expression acts as an unfavorable survival marker, although some lineages such as UCEC and COAD show a favorable association.

READ, LUAD, and UCEC are the cancer types where WDR47 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Median	III,IV	0.059	0.761	<.001	12	view →
LUAD	DFS	Median	II,III,IV	0.178	0.721	.008	12	view →
UCEC	DFS	Median	All	0.954	0.828	.026	4	view →
COAD	DFS	Median	IV	1.000	0.266	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

WDR47–READ (DFS)

Open the READ breakdown →