WDR47

Across TCGA pan-cancer cohorts, WDR47 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated WDR47 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher WDR47 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated WDR47 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where WDR47 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	IV	0.908	0.229	.010	19	view →
LUAD	DFS	Median	III,IV	0.303	0.704	.006	13	view →
LSCC	DFS	Quartile	II,III,IV	0.939	0.627	.014	12	view →
GBM	DFS	Quartile	All	0.901	0.615	<.001	10	view →
HNSC	DFS	Tertile	II,III,IV	0.991	0.883	.012	10	view →
PDAC	DFS	Quartile	III,IV	0.300	0.905	.006	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

WDR47–CCRCC (DFS)

Open the CCRCC breakdown →