Across TCGA patient cohorts, WDR46 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,672 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDR46-associated proteins across cancer lineages are ABCF1, SRPK1, and CTNNBL1. Each is linked with WDR46 in more than 6 cancer types. Because this analysis shows association rather than direction, both WDR46-to-partner and partner-to-WDR46 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR46→partner) and Y-score (partner→WDR46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ABCF1 →	+0.284	+0.525	<.001	<.001	3	7
OV	SRPK1 →	+0.445	+0.580	<.001	.001	3	6
OV	CTNNBL1 →	+0.265	+0.598	<.001	<.001	3	6
OV	DAXX →	+0.296	+0.560	<.001	<.001	3	6
OV	DHX16 →	+0.268	+0.463	<.001	.002	3	6
OV	HSP90AB1 →	+0.358	+0.512	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,672 associations by consensus.

Exploration

WDR46 survival (RNA) · tumor vs normal (RNA) · all WDR46 data types